Your gut-brain axis is tunable. Here's how to find out.
Studies tell you what happened on average to other people. An n-of-1 experiment tells you what happens to you. Pick one change, log how you feel each day, and let your own data speak.
Start your first experiment → Simulate it first →
New: before you commit weeks to a real experiment, dry-run it in the Neurobiome Model — an in-silico gut-brain axis that projects how your protocol should move your microbes, mood, sleep and focus over time.
Pick one lever
A fermented food, a fibre, a specific probiotic strain, a sleep or breathwork routine. One at a time — that's what makes it readable.
Log daily, 10 seconds
Rate mood, gut comfort, and sleep 1–5 each day. Consistency beats precision.
Read your trendline
After a few weeks, your own curve appears. Share it if you want to help others — or keep it private.
Public experiments
Time-restricted eating & bloating
10-hour window
Bone broth & gut comfort
daily cup
Morning light + gut routine
10 min AM light + breakfast fiber
Sauerkraut daily
2 tbsp with lunch
Polyphenols & mood (berries, cocoa)
daily polyphenol foods
Fiber diversity vs. IBS flares
widen fiber sources
Cutting ultra-processed, 30 days
whole-food swap
Butyrate foods & brain fog
fiber + fermented, tracked clarity
Fermented foods, 6 weeks
one fermented portion daily
B. longum 1714 before big meetings
strain on high-stress days
Low-FODMAP reset then reintroduce
structured elimination
Kimchi & regularity
small portion daily
Prebiotic fiber ramp
slow inulin/GOS increase
Reducing coffee & anxiety
1 cup cap before noon
Rebuilding after antibiotics
multi-strain + prebiotic, 8wk
L. rhamnosus & morning anxiety
single-strain probiotic, AM
30+ plants a week for steadier mood
count plant varieties, target 30/wk
Resistant starch & afternoon energy
cooled potato/oats daily
Psychobiotic blend & sleep
evening multi-strain
Self-experimentation is for learning about your own body, not for diagnosing or treating illness. Change one thing at a time, keep your clinician in the loop, and stop anything that makes you feel worse.